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Most recently, a novel inhibitor, Ferfluor-1, was designed using a bioisosteric replacement strategy, resulting in an 8- to 40-fold increase in half-life and enabling blood-brain barrier (BBB) penetration (Yan et al., 2025)

Nat Rev Gastroenterol Hepatol 18(2):8384 Nishida A, Inoue R, Inatomi O, Bamba S, Naito Y, Andoh A (2018) Gut microbiota in the pathogenesis of inflammatory bowel disease

In patients with iron overload state, total body iron can be lowered by chelation in patients who are anemic and by phlebotomy in those who are not

Havir EA, McHale NA

The scalp's many nerve endings make it sensitive to irritating substances, and high copper peptide concentrations can trigger inflammation responses

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